منابع مشابه
epigenetic brca2 gene in epithelial ovarian cancer
background ovarian cancer is the most common fatal gynecologic malignancy in women. the brca2 gene has a role in regulation of cell cycle during proliferation, differentiation and dna repair. changes in the methylation of brca2 may be an effective mechanism for ovarian cancer. objectives the aim of the present study was to evaluate the association between ovarian cancer and methylation status o...
متن کاملEpithelial ovarian cancer.
Ovarian neoplasms consist of several histopathologic entities, and treatment depends on the specific tumor type. Epithelial ovarian cancer comprises most malignant ovarian neoplasms (~ 80%)1; however, other less-common pathologic subtypes must be considered in treatment guidelines. The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Ovarian Cancer discuss epithelial ovarian ...
متن کاملEpithelial Ovarian Cancer Cells
Elucidation of the mechanisms responsible for aberrant phosphatidylcholine (PC) metabolism in cancer cells may allow identification of novel biomarkers of tumor progression and design of new targeted anticancer therapies. We recently reported up-regulation of PC-specific phospholipases in epithelial ovarian cancer cells (EOC) compared with nontumoral (normal or immortalized) counterparts (EONT)...
متن کاملserum her2 level in epithelial ovarian cancer
introduction : the proto-oncogene her2 plays a key role in the control of cellular proliferation. its overexpression has been reported to be associated with a poor prognosis in cancer, particularly in breast cancer. materials and methods : in the present study, serum her2 levels were investigated in patients diagnosed with epithelial ovarian cancer. serum her2 levels were detected by an elisa c...
متن کاملIrinotecan in epithelial ovarian cancer.
Ovarian cancer, the second most common gynecologic malignancy, accounts for approximately 14,000 deaths annually in the United States. Disease relapse after primary treatment, which consists mainly of surgery followed by platinum-based therapy, occurs in more than 60% of ovarian cancer patients overall, and in more than 80% of those diagnosed initially with advanced-stage disease. Responses to ...
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ژورنال
عنوان ژورنال: memo - Magazine of European Medical Oncology
سال: 2020
ISSN: 1865-5041,1865-5076
DOI: 10.1007/s12254-020-00608-x